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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3df0727fc39526f45ec67a0ecae4849c1fe32e1ee02169cb71952bd649edffe' 
  AND token = 'RCffQKIpMsO27ykeMvqh3yWjPgBr45c+vj+xZ0zDsSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}