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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a567e651c85013693d8c4f047a1a7f60ac6cae0b0cd82892cab5b4f0a990fa6' 
  AND token = 'kA+1d3Xl+ckQPFQY6g7qn12HpLjZVePHQWCJ6pvNlSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}