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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e33bd06429cef76072f3be775ab680d2cf7a2589cb546b40a0bd4cf14e3f5d6' 
  AND token = 'fmDSsNUxorvWrCH3YAZ92Cniun40B/KAGlFA/88rVNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}