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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38ce0e76682ad207edef00e07d539a0e0f6138c991a1db33c9f1d503f5943797' 
  AND token = 'si/BM+ipZvQb8hHQNNaFfejxP9AIiY0AOxeUeIQ4PIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}