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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdda81e4ca1a1f2ef2a83d4ca8cf703b211dd08583c03e764827d1402bb93245' 
  AND token = 'TzfReK7B9i4KleOViHpfKQLM7qxFNMyji8qiWgUmZes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}