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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9abe8a44d294a37c99f3c5d1174c8be4bc99fafb433b7439c249c3ff8fc8bebf' 
  AND token = 'zDu/T7k59pUlbovdwq0z4aO3fuJc5VjjJ/KTfVctzXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}