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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43fa711524ec803de75ed6c04e40fe8379b106edbc5cabe5ccb4e31d03ea6b97' 
  AND token = 'obRZmsQlCSY8sqnNMecAFyw1E4TkxPip965a/cLLwnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}