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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42d92b0ab3415e3f6f1b8fde144df704daa561fa353ea9326005c31b09bfebf8' 
  AND token = 's7wZbsAWSgLrv3jdONlBnyqaPxfRhcgAhVMfsgXF8fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}