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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21422f43d3d5a38524e1d517f4311a3b101ba3b15015c6445e8fb72df374b981' 
  AND token = 'klqc39AyEDNOo8ojgbNMNuEY39bP1R28YMFfXS3dwp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}