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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0da340eb52d0a81c5d56ae523c6ef65df6165b10c9ce2289457a8f55b25820' 
  AND token = 'I5V8FmVDEBJwvBCXzx3LbdIXs8TYsBauyzRVauls2Nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}