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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7bed83f8c99689d98bf6d1d0791a0e88647b9ae7bd96899c78d38f4e7e9df28' 
  AND token = '/Kq9UsnU/ByT0WrGhPOKNOOcPYRKYE1byvP0uobmkRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}