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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bb45c447274d5882de5c9647cfcb84d8abf9d2f92d3aa0ac0736eb4864b694' 
  AND token = '9nJsXmhuIW1339owejntBnJSHUpmK9zij6tH6j4fCik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}