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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d64b6104eef932cf48653d91d070fa1208c4f0309af67f1d8978c5e6ff1edd9' 
  AND token = 'XtaNa1pnSmWAyh0MJYLmZdyva05UM23CUO5X7UfYoaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}