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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38b39bad8643d2e0523f9409b482e4e6f61db2a5a60ec41065f0702999c3b1cf' 
  AND token = 'XqF8Jq+PMDa6ynjp/9PR6OmOfh8bnToFv52gzbfvwiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}