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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b063a6e9f928d7286cc2232489ad7db31cccbecc4412bdb97ccf4f9cbd18b5a' 
  AND token = 'CxqbxXUh66hZezLdb+tD/EU6HLDprMC0GihRlqvBMfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}