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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ead4f0bef87987f0bbf4e41068b42eaf273ab20da31e3bd51f32c520668b0251' 
  AND token = 'ytBiCou1/pPt8d8lp0a0fBeCzWlc7hmG3k5jZWGHHkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}