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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2853c070c8c015b0e4cce507c575e556fef8a46d9cc4a754461e60ba43df69f0' 
  AND token = 'IeZnAZ0Gi7vFOjkxZDJGkUuD91J8Y9uIey8mcz50Dss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}