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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b2feda7d6d84d92d40ca8df574d75868610dec6749dbed79c3c58db464f5228' 
  AND token = '1ocgdiy0QjxhxtkuYa911N81enipeGfOizKHuZbw+9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}