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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a4860814f40cd74b289ab5a737a286ab6fb661e09c6872d21fbc2e28710afd' 
  AND token = '8bIOIvAuu/B2N83K5ptbWcTdoCT4DEzDUOjnyzylWTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}