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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc0074ec7dc418e71b5deeed8cd764f8361969ca68ab300dd7d115aecaa79b22' 
  AND token = 'ZxZKFb0hI3Tx7KGc/JCwmcXXLVSDqa+oWW8S2i5mYQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}