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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10997593a95263f0586e82f31305d155ac7f09da3162581559a87ce4b2f736d1' 
  AND token = 'mQX8y1TVulUUqvHl2uqhzW6E/d+niiK0rXTb+S0lkfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}