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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5143fa2e4d3f8486c629278d107509295435c145f6a9dd3383bfcbee6eb0aea1' 
  AND token = '+Pcu0ZWu3yOuuPdSd8DBl9QPr+gNhoTzq2YvGebjo38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}