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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ce6307e658280c40eff2db9bcb51a7e57e824fb1acecddb9ef94df8fbb0ad8f' 
  AND token = '8csGbFOF6HXmdRMThy3gmBrtgpc4MdpQ6LCeE7h+Nx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}