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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74be270abef6e04140db23f7c89c2ddd218625e49363cff81ef80dce9ab60d5f' 
  AND token = 'HMMS1EPe8FHkq0IYfadnHic2H935cvK00c5zTjwqHB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}