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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e16f1b05a95ac3eefc0d8362197afa386e24848478bc0166429135a868c9b8bc' 
  AND token = 'Jf9KDxSUvoyG3YTYyo4cNY3sycM7eOyxpvKgyxmFxc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}