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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6af52859357768c5f898682b70786ce122333930221bf107ae9b04799d3f1d4b' 
  AND token = '6O4+w6Msly3NeXJWII8qAHpwLE3gKijaoSulRdM+DU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}