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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4f97187be51fce1c6843090d9dfbc21e199fb00267f53f227a411d414d5d9c7' 
  AND token = 'RTtvHkwGzzVnvzQSj8yxuQLTvBHEYEay8S3wxjTEUI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}