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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1ea4ade57a2ba6a037854e0a42185a755d52169fbc57df6ab2401203b58c61c' 
  AND token = '1Oepm2my16PvkrW40naHmbd2xkFfWZ6oGmBNM4Inv/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}