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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87569728b75011a71f2089382223937a3918c2b5c3902324349942cd5ef9bc0f' 
  AND token = 'FpDS5tN2jN9sBqUlHDaNfp1HkLKGwfzj1k3cvAr4LGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}