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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '739ce13803d8d4629a71280dadf354ad8542ade0d34ab3ac40b20ff731475ba9' 
  AND token = 'lAPbDDVkWTA0tVuMAzmzZWjDWqxMW+ViEIdAk5n4VbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}