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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2845a20da42add15c7b1492a3cd586c4cb5796a5cbd23d082eaf6a388a5581ca' 
  AND token = 'D0wnIq7Oufkr3NbnQAtre/2+IXsss4tVWfBoX6wARq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}