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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '841fa643906adf0b401e1d16f0f3b7decf70c1c77386b7ad8acff9c8036a4bff' 
  AND token = 'rG4y/4PpInAzx8paDkw5CvNFTe4BEH/EDJMgSxAaM74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}