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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81dda24397c65ad2fc5788f513023a1ed75c62c209dd6b3da344ed8f12401281' 
  AND token = 'ETJtqj7Sdv8MXRO0BLb+QWPp7Z+KtbVeJ81/qvkD3vE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}