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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de0dad65d323e4b5c9c8b8486652dba1cf3a893579c79b373ea4fadf9c19094c' 
  AND token = 'ArPfcfkv67QX42+1pcAG5wdGE5/HDSN7Vm5CXM/1bMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}