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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b0d47f89708098926c08737f1a5eb6589b414e82f027462803019b1bb7e2edb' 
  AND token = 'yNuQ5SCm55LyPWLR/9M8+C5EbpO+aFyp1K9nXxPFmaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}