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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7388b1100933e4e1b029b523279c36780e52511022b3e311a2a1a0368e2e6fe' 
  AND token = 'G8M4zX2IX9GLsv0X8jrC2rldyZRbeW04WSSgYI3jMGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}