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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ffebc99142aa9a6415a39481db75e85fd4602b9e06b4c684d8e50679d5336ec' 
  AND token = 'b+et9ncjelEu/mxBrjmATT88cIAqfYfFdDmLB2+kPRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}