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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '770b6ce2f5d2a07bdfad5110f3b3e778282e3a426ff5fcec036b740424cd1e33' 
  AND token = 'f7bM2HoO8Ikx/TRxjvoMYEoAh6jHwpTRfGqIwOnVEJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}