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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da0743352eefd6a077378a2daf1724345e66c11c4cda1432a513731471214add' 
  AND token = 'fFX8x0bOTo3tUf9GcZ1BdrO0flnC1SyNYs06XhLemII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}