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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4abc24208450d0dfd722d0397ce3c1c634bac89de4f71b420e10b994266dad0' 
  AND token = 'U1KwLmrjN5aSCSL7NS8wxaXTXcy87opjLfY/6oD1SDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}