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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd64443d168ab37b5172efb601b5ce470bc06e13d47670a4547ff2f6c89c0e268' 
  AND token = '0NFC9dqDyKCC13v1+DNHDkAZ+yWW491KCN3flV9lh58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}