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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746388edc82bbe1dbca271db6e20b209e77c417c7691c0f96472d473ff1922b1' 
  AND token = '5Dt2EfrixXFwP+Rt6PzAILqirFx2B5RZrBi9OlCFg0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}