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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8c7f33eeac7e9c26925619272f0d808b282a308ecaeaa0fed3900a8aaf6b5bc' 
  AND token = 'PCapnuR0Hp3UPM4xUJZ8mYPKqO0WPxRliry4dt4te9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}