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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4c878e4180563f5d017f1da0c45040e87cd2cd6c7bc8f5082e6dc3450aad665' 
  AND token = 'AtEUf6vfNP2byE+eIy+KsqFBDbiqz949M7YqmkdatQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}