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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6292c59399ab5d2a67d89bb4d16af993e36a58dde945b802d7bc62d4c3f1143f' 
  AND token = 'cMgQPaJ27EDgiigBhwke1CeN765qHmeCyn27n0R1gmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}