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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf2da036b3053dc17837e155a2b25ad65ec5b63a8d467a261284b387cce18064' 
  AND token = 'tY7lQR/rTHHdHTOwIYQtB5Zn0wA1mlOI5M20liVHD8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}