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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '961f130133cf498fd4df1674c962a532631f57172a054f282dfa43d1c1051280' 
  AND token = 'JPpkksnvDmONHkzvgTRgPznbJPWyhX7C23VJ9lvceYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}