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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dc0a6b5517d0c20cb5ac64233a3144766bbc93c55e639d69724b207c618717e' 
  AND token = 'I9Ep/CAB+V9jeCmgiZaUF+Ru2LeObtXPt45qb6PnTg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}