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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd38fb1b472a35ae924ab94f30a5edb8974de1670bfc49294a31e035a9c01a9c' 
  AND token = 'XHAma1njbsPN2yAvovWGCZ0+NY7BdnN36bQdCmfclnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}