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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6f99e03b2bc01a6ce3dd1300c72f0372a3dbb563bbbc5f1884b3739766ecc88' 
  AND token = 'mBM72EojlboWZOaAKtEwgPPQz1UJhrZAf90/2Tm68vA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}